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New technique helps researchers determine how stem cells differentiate

Apr 6, 2017

Stem cell differentiation can now be seen thanks to a combination of machine learning and microfabrication techniques developed by scientists at the RIKEN Quantitative Biology Center in Japan. The results, published in PLOS ONE, followed the differentiation of human mesenchymal stem cells (MSCs) which are easily obtained from adult bone marrow.

agarose microstructures
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  1. N. Tanaka, T. Yamashita, A. Sato, V. Vogel, and Y. Tanaka: "Simple agarose micro-confinement array and machine-learning-based classification for analyzing the patterned differentiation of mesenchymal stem cells", PLOS ONE, doi: 10.1371/journal.pone.0173647