Measuring morphogenesis of organs
A new statistical-based method provides insight into how developing organs morph into their mature shapes
Sep 15, 2017 Tweet

By merely measuring the positions of fewer than one in ten cells in a developing organ, scientists can reconstruct how the entire organ acquires its shape thanks to a statistical analysis method developed by QBiC's Yoshihiro Morishita and colleagues[1]. This method will advance our understanding of organ growth by overcoming the limitations of traditional imaging.
- Morishita, Y., Hironaka, K., Lee, S.-W., Jin, T. & Ohtsuka, D. "Reconstructing 3D deformation dynamics for curved epithelial sheet morphogenesis from positional data of sparsely-labeled cells" Nature Communications 8, 15 (2017). doi: 10.1038/s41467-017-00023-7